The
condition means patients develop a rash of small, incredibly itchy bumps
(urticaria means hives) in response to a range of unusual and diverse
triggers.
Many
are allergic to weather, and develop hives in hot and cold
temperatures, while others break out in response to exercise, or even
pressure on their skin such as a bag
on their shoulder or even a tight
bra strap. More rarely, some people with physical urticaria develop the
rash in response to water, or even sunlight.
However,
in many cases, especially where the symptoms are not severe, people
think they have reacted to something they have eaten, or have used on
their skin.
The hives are triggered by the chemical histamine, which is released in the body during an allergic reaction.
The
problem can start at any age. Harry first started to develop rashes at
three months old, says his mother Lisa, a 39-year-old GP practice
manager. 'The first time it happened he woke at 3am covered in the rash
and screaming,' she recalls. 'But it cleared up within an hour, so by
the time we got him to the doctor there was nothing to see.
'We
initially thought it was the soap or shampoo he was allergic to, but
even when we just used water to bathe him he would still get the rash.'
He also got a rash round the waistband of his nappy.
Lisa was
then alarmed to see something as innocuous as bad weather would trigger a
rash. 'When the weather was really cold he'd start to get a rash within
a few minutes that would spread over his body.
'He would also get the rash in hot weather. He'd just scream and try to scratch it.'
The
family took Harry to the doctor multiple times over the next year, but
were told it was simply a virus (the condition didn't affect his older
brother, Oliver, now six). At six months Harry was diagnosed with
multiple food allergies, including to egg and dairy, which doctors
thought might have triggered the rash. But he continued to get the rash
even after avoiding those foods.
Out
of desperation, Lisa and her husband Eddie, 66, who live in Walsall,
West Midlands, took Harry to Great Ormond Street Hospital in London
where they paid to see a private specialist - and Harry was diagnosed
with physical urticaria.
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